Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | CTSV | O60911 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12622630 | 0.94 | SMPD1 (0.53) | NPC1RAB9AHPGDSMN1; SMN2KMT2A | |
| SCHEMBL19483249 | 0.92 | MRGPRX4 (0.55) | NPC1RAB9AHPGDSMN1; SMN2MEN1 | |
| SCHEMBL12251439 | 0.86 | KDM4E (0.53) | HPGDSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL12251438 | 0.86 | KDM4E (0.53) | HPGDSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL17106561 | 0.84 | NPC1 (0.49) | NPC1RAB9AHPGDSMN1; SMN2MEN1 | |
| SCHEMBL12295554 | 0.84 | MRGPRX4 (0.68) | RAB9ASMN1; SMN2KDM4EMRGPRX4ALDH1A1 | |
| SCHEMBL22387608 | 0.84 | KMT2A (0.56) | NPC1RAB9AHPGDSMN1; SMN2MEN1 | |
| SCHEMBL12024746 | 0.83 | MRGPRX4 (0.56) | RAB9ASMN1; SMN2KDM4EMRGPRX4CYP2C9 | |
| SCHEMBL12772068 | 0.83 | MRGPRX4 (0.52) | RAB9ASMN1; SMN2MRGPRX4RXRARXRB | |
| SCHEMBL12303223 | 0.82 | MRGPRX4 (0.47) | NPC1RAB9AHPGDSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10202410-B2 | Scaphopetalone analogs and their uses | BRIGHAM YOUNG UNIVERSITY (US) | 2019-02-12 | — | — | US | disclosed |
| US-20170152280-A1 | SCAPHOPETALONE ANALOGS AND THEIR USES | BRIGHAM YOUNG UNIVERSITY | 2017-06-01 | — | — | US | disclosed |
| US-20040082578-A1 | Arylindenopyridines and related therapeutic and prophylactic methods | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10202410-B2 | Scaphopetalone analogs and their uses | MUSK, SHBG, CYP17A1 | NPC1 4089/4885RAB9A 2146/4885HPGD 1683/4885 |
| US-20040082578-A1 | Arylindenopyridines and related therapeutic and prophylactic methods | ADORA2A, ADORA1, PDE2A | NPC1 1354/4885RAB9A 2212/4885HPGD 547/4885 |
| US-20170152280-A1 | SCAPHOPETALONE ANALOGS AND THEIR USES | MUSK, SHBG, CYP17A1 | NPC1 4089/4885RAB9A 2146/4885HPGD 1683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.