Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 10/20 | 0.71 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.71 |
| ▸ | GRIN2D | O15399 | 9/20 | 0.71 |
| ▸ | GRIN3B | O60391 | 9/20 | 0.71 |
| ▸ | GRIN2A | Q12879 | 9/20 | 0.71 |
| ▸ | GRIN2C | Q14957 | 9/20 | 0.71 |
| ▸ | GRIN3A | Q8TCU5 | 9/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4409737 | 0.83 | GRIN1 (1.00) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4421110 | 0.82 | GRIN1 (0.83) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL1384919 | 0.77 | GRIN1 (0.65) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4577390 | 0.74 | GRIN1 (1.00) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4576737 | 0.74 | GRIN1 (0.82) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4412053 | 0.73 | GRIN1 (1.00) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL12508969 | 0.71 | GRIN1 (0.57) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL12508754 | 0.71 | GRIN1 (0.68) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL1381735 | 0.69 | GRIN1 (0.63) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4552245 | 0.68 | GRIN2D (0.83) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409477-B1 | PIPERIDINE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON NYRT (HU) | 2008-09-17 | — | — | EP | claimed |