Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4961791 | 0.86 | RXRA (0.52) | MRGPRX4PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL4964669 | 0.84 | HDAC8 (0.50) | MRGPRX4ALOX5APMAPTMAOBHTT | |
| SCHEMBL5781307 | 0.79 | MRGPRX4 (0.47) | MRGPRX4ALOX5APMAPTMAPK1TDP1 | |
| SCHEMBL6885785 | 0.79 | PTGER1 (0.49) | MRGPRX4PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL16548414 | 0.79 | MRGPRX4 (0.53) | MRGPRX4PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL4963469 | 0.78 | MRGPRX4 (0.52) | MRGPRX4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL5774987 | 0.78 | GCK (0.47) | MRGPRX4PTGER1ALOX5APMAPTMAPK1 | |
| SCHEMBL4962160 | 0.77 | MRGPRX4 (0.43) | MRGPRX4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL7088529 | 0.77 | KDM4E (0.44) | MRGPRX4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL6887813 | 0.76 | PTGER1 (0.61) | MRGPRX4PTGER1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114828-B1 | N-ALKYLASPARTYLDIPEPTIDE ESTER DERIVATIVES AND SWEETENERS | AJINOMOTO KK (JP) | 2008-03-12 | — | — | EP | disclosed |
| US-7238830-B2 | N-alkylaspartyl dipeptide ester compounds | AJINOMOTO CO., INC. (JP) | 2007-07-03 | — | — | US | disclosed |
| US-20010039357-A1 | N-alkylaspartyl dipeptide ester compounds | AJINOMOTO CO., INC. (JP) | 2001-11-08 | — | — | US | disclosed |
| EP-1114828-A1 | N-ALKYLASPARTYLDIPEPTIDE ESTER DERIVATIVES AND SWEETENERS | Ajinomoto Co., Inc. (JP) | 2001-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010039357-A1 | N-alkylaspartyl dipeptide ester compounds | DNPEP, ANPEP, ASNS | MRGPRX4 1939/4885PTGER1 4231/4885PTGER4 3714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.