⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4963577 | 1.00 | — | — | |
| SCHEMBL13533918 | 1.00 | — | — | |
| SCHEMBL7994660 | 0.93 | MAPT (0.43) | — | |
| SCHEMBL7993708 | 0.85 | — | — | |
| SCHEMBL199063 | 0.81 | — | — | |
| SCHEMBL199062 | 0.81 | — | — | |
| SCHEMBL1633550 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL28366662 | 0.79 | ACE (0.46) | — | |
| Ammonia Solution, Strong SCHEMBL27857098 | 0.79 | ACE (0.46) | — | |
| Hydrochloric Acid SCHEMBL28366660 | 0.79 | ACE (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050159363-A1 | Selective neuronal nitric oxide synthase inhibitors | SILVERMAN RICHARD B (US) | 2005-07-21 | — | — | US | claimed |
| US-6803486-B2 | PEPTIDOMIMETIC; N-AMINOBUTYL-N'-NITROGUANIDINE DERIVATIVES | NORTHWESTERN UNIVERSITY | 2004-10-12 | — | — | US | claimed |
| US-20030119751-A1 | Selective neuronal nitric oxide synthase inhibitors | NORTHWESTERN UNIVERSITY | 2003-06-26 | — | — | US | claimed |
| WO-2003000198-A2 | SELECTIVE NEURONAL NITRIC OXIDE SYNTHASE INHIBITORS | NORTHWESTERN UNIVERSITY (US) | 2003-01-03 | — | — | WO | claimed |
| CN-116239591-A | (4R) -sulfonamido-L-prolinamide compound, preparation method, application and pharmaceutical composition thereof | 嘉兴学院 | 2023-06-09 | — | — | CN | disclosed |
| US-11573224-B2 | Methods of detection using X-ray fluorescence | ICAGEN, LLC (US) | 2023-02-07 | — | — | US | disclosed |
| CN-104004018-B | Single-stranded nucleic acid molecule having nitrogen-containing alicyclic skeleton | 株式会社博纳克 | 2017-01-04 | — | — | CN | disclosed |
| CN-104059911-B | single-stranded nucleic acid molecule having nitrogen-containing alicyclic skeleton | 株式会社博纳克 | 2017-01-04 | — | — | CN | disclosed |
| CN-103052711-B | Single-stranded nucleic acid molecule having nitrogen-containing alicyclic skeleton | 株式会社博纳克 | 2016-08-03 | — | — | CN | disclosed |
| US-7470815-B1 | Selective neuronal nitric oxide synthase inhibitors | NORTHWESTERN UNIVERSITY (US) | 2008-12-30 | — | — | US | disclosed |
| US-20050159363-A1 | Selective neuronal nitric oxide synthase inhibitors | SILVERMAN RICHARD B (US) | 2005-07-21 | — | — | US | disclosed |
| CN-1170604-C | Electrotransport device including a compatible antimicrobial agent | — | 2004-10-13 | — | — | CN | disclosed |
| US-6803486-B2 | PEPTIDOMIMETIC; N-AMINOBUTYL-N'-NITROGUANIDINE DERIVATIVES | NORTHWESTERN UNIVERSITY | 2004-10-12 | — | — | US | disclosed |
| US-20030119751-A1 | Selective neuronal nitric oxide synthase inhibitors | NORTHWESTERN UNIVERSITY | 2003-06-26 | — | — | US | disclosed |
| WO-2003000198-A2 | SELECTIVE NEURONAL NITRIC OXIDE SYNTHASE INHIBITORS | NORTHWESTERN UNIVERSITY (US) | 2003-01-03 | — | — | WO | disclosed |