Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28750763 | 0.92 | ALDH1A1 (0.51) | ALDH1A1HSD17B10TSHRMEN1KMT2A | |
| SCHEMBL28351176 | 0.83 | HSD17B10 (0.41) | ALDH1A1HSD17B10TSHRMEN1KMT2A | |
| SCHEMBL31228725 | 0.81 | TSHR (0.52) | ALDH1A1HSD17B10TSHRCA12CA1 | |
| SCHEMBL28126645 | 0.81 | TSHR (0.55) | ALDH1A1HSD17B10TSHRMEN1KMT2A | |
| SCHEMBL23013457 | 0.79 | NUDT1 (0.51) | ALDH1A1HSD17B10TSHRMEN1KMT2A | |
| SCHEMBL27571353 | 0.78 | MAPT (0.52) | ALDH1A1HSD17B10TSHRMEN1KMT2A | |
| SCHEMBL3470803 | 0.78 | MEN1 (0.52) | ALDH1A1TSHRMEN1KMT2ALMNA | |
| SCHEMBL55681 | 0.77 | ALDH1A1 (0.61) | ALDH1A1HSD17B10TSHRMEN1KMT2A | |
| SCHEMBL27883893 | 0.76 | ALDH1A1 (0.59) | ALDH1A1HSD17B10TSHRMEN1KMT2A | |
| SCHEMBL14358812 | 0.75 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1901708-A1 | PERCUTANEOUSLY ABSORPTIVE OPHTHALMIC PREPARATION COMPRISING OLOPATADINE | Senju Pharmaceutical Co., Ltd. (JP) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007007863-A1 | PERCUTANEOUSLY ABSORPTIVE OPHTHALMIC PREPARATION COMPRISING OLOPATADINE | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2007-01-18 | — | — | WO | disclosed |