Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146376 | 0.90 | KDM4E (0.50) | ALDH1A1HSD17B10KDM4EPPARGPPARA | |
| SCHEMBL29608063 | 0.90 | KDM4E (0.50) | ALDH1A1HSD17B10KDM4EPPARGPPARA | |
| SCHEMBL288855 | 0.90 | KDM4E (0.50) | ALDH1A1HSD17B10KDM4EPPARGPPARA | |
| SCHEMBL198219 | 0.90 | KDM4E (0.50) | ALDH1A1HSD17B10KDM4EPPARGPPARA | |
| SCHEMBL15023884 | 0.79 | ALDH1A1 (0.44) | ALDH1A1HSD17B10KDM4EMAPTHPGD | |
| SCHEMBL29643354 | 0.78 | PRNP (0.41) | ALDH1A1HSD17B10KDM4ECYP2C19MEN1 | |
| SCHEMBL28581258 | 0.78 | PRNP (0.41) | ALDH1A1HSD17B10KDM4ECYP2C19MEN1 | |
| SCHEMBL27165013 | 0.76 | KDM4E (0.39) | ALDH1A1HSD17B10KDM4EMAPTHPGD | |
| SCHEMBL7287554 | 0.76 | KDM4E (0.53) | ALDH1A1HSD17B10KDM4EHPGDPPARG | |
| SCHEMBL17545257 | 0.76 | CYP1A2 (0.48) | ALDH1A1HSD17B10KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891106-A2 | NOVEL COMPOUNDS AS GLP-I AGONISTS | CADILA HEALTHCARE LTD. (IN) | 2008-02-27 | — | — | EP | claimed |
| WO-2007017892-A2 | NOVEL COMPOUNDS AS GLP-I AGONISTS | CADILA HEALTHCARE LIMITED (IN) | 2007-02-15 | — | — | WO | claimed |
| EP-1891106-A2 | NOVEL COMPOUNDS AS GLP-I AGONISTS | CADILA HEALTHCARE LTD. (IN) | 2008-02-27 | — | — | EP | disclosed |
| WO-2007017892-A2 | NOVEL COMPOUNDS AS GLP-I AGONISTS | CADILA HEALTHCARE LIMITED (IN) | 2007-02-15 | — | — | WO | disclosed |