Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 7/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3293923 | 0.85 | P2RY14 (0.39) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL4544182 | 0.80 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL4544174 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL3288612 | 0.80 | DDB1 (0.43) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL14019651 | 0.79 | CNR2 (0.40) | KDM4EPPARGPPARALMNAHTT | |
| SCHEMBL4030026 | 0.79 | KDM4E (0.42) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL13799088 | 0.78 | KDM4E (0.42) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL14019666 | 0.78 | CNR2 (0.42) | PPARGPPARACNR2 | |
| SCHEMBL5005805 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL3292992 | 0.78 | P2RY14 (0.38) | KDM4EALDH1A1HPGDTSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879903-A1 | ETHER LINKED MACROLIDES USEFUL FOR THE TREATMENT OF MICROBIAL INFECTIONS | GlaxoSmithKline istrazivacki centar Zagreb d.o.o. (HR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006120541-A1 | ETHER LINKED MACROLIDES USEFUL FOR THE TREATMENT OF MICROBIAL INFECTIONS | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (US) | 2006-11-16 | — | — | WO | disclosed |