Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4961660 | 0.91 | PPARG (0.45) | KDM4EALDH1A1LPAR1PPARGPPARA | |
| SCHEMBL4961998 | 0.86 | KDM4E (0.43) | KDM4EALDH1A1HTR2A | |
| SCHEMBL4964263 | 0.85 | HSP90AA1 (0.44) | KDM4EALDH1A1 | |
| SCHEMBL4961989 | 0.83 | ALDH1A1 (0.50) | KDM4EALDH1A1PPARGPPARAHTR2A | |
| SCHEMBL4964280 | 0.82 | KDM4E (0.46) | KDM4EALDH1A1LPAR1PPARGPPARA | |
| SCHEMBL4964260 | 0.77 | KDM4E (0.39) | KDM4EALDH1A1LPAR1PPARGPPARA | |
| SCHEMBL4965190 | 0.73 | HTR2A (0.43) | ALDH1A1LPAR1LPAR5HTR2A | |
| SCHEMBL4630408 | 0.70 | LTB4R2 (0.48) | PPARGPPARAHTR2A | |
| SCHEMBL4629932 | 0.70 | HTR2A (0.49) | LPAR1PPARGPPARALPAR5HTR2A | |
| SCHEMBL4963240 | 0.69 | PPARD (0.44) | LPAR1PPARGPPARALPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517679-B1 | ORTHO-SUBSTITUTED BENZOIC ACID DERIVATIVES FOR THE TREATMENT OF INSULIN RESISTANCE | ASTRAZENECA AB (SE) | 2008-02-13 | — | — | EP | disclosed |