SCHEMBL496438

SCHEMBL496438

O=C1OC(=O)c2cc(C(F)(c3ccc4c(c3)C(=O)OC4=O)C(F)(F)C(F)(F)F)ccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 2/20 0.40
NPC1 O15118 2/20 0.33
CASP3 P42574 2/20 0.33
RAB9A P51151 2/20 0.33
SENP8 Q96LD8 2/20 0.33
SENP7 Q9BQF6 2/20 0.33
SENP6 Q9GZR1 2/20 0.33
PLA2G1B P04054 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33
TDP2 O95551 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA4 P22748 1/20 0.31
CA7 P43166 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12731650 0.89 ALOX15 (0.43) ALOX15TDP1ALDH1A1NPC1CASP3
SCHEMBL17119191 0.86 ALOX15 (0.40) ALOX15TDP1ALDH1A1NPC1CASP3
SCHEMBL15914778 0.84 ALOX15 (0.39) ALOX15TDP1ALDH1A1NPC1CASP3
SCHEMBL20477107 0.84 ALOX15 (0.34) ALOX15TDP1ALDH1A1TYMS
SCHEMBL17118704 0.83 ALDH1A1 (0.39) ALOX15TDP1ALDH1A1NPC1CASP3
SCHEMBL49774 0.81 ALOX15 (0.43) ALOX15TDP1ALDH1A1NPC1CASP3
SCHEMBL16626117 0.81 ALOX15 (0.46) ALOX15TDP1ALDH1A1NPC1CASP3
SCHEMBL1498509 0.81 ALOX15 (0.46) ALOX15TDP1ALDH1A1NFKB1NFKB2
SCHEMBL14536450 0.81 ALOX15 (0.46) ALOX15TDP1ALDH1A1NPC1CASP3
SCHEMBL10493880 0.79 TDP1 (0.42) ALOX15TDP1ALDH1A1NPC1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240191028-A1 COMPOSITION FOR MANUFACTURING POLYIMIDE FILM AND POLYIMIDE FILM FOR FLEXIBLE METAL CLAD LAMINATE MANUFACTURED USING THE SAME NEXFLEX CO., LTD. (KR) 2024-06-13 US claimed
WO-2023200025-A1 COMPOSITION FOR PRODUCING POLYIMIDE FILM AND POLYIMIDE FILM FOR FLEXIBLE METAL CLAD LAMINATE PRODUCED USING SAME 주식회사 넥스플렉스 2023-10-19 WO claimed
EP-4028448-A1 POLYMER LAYERS BY REACTIVE PRINTING Heraeus Deutschland GmbH & Co. KG (DE) 2022-07-20 EP claimed
WO-2021048219-A1 POLYMER LAYERS BY REACTIVE PRINTING HERAEUS DEUTSCHLAND GMBH & CO KG (DE) 2021-03-18 WO claimed
EP-2159247-B1 Solvent-free polymide silicone resin compositions and cured products thereof SHINETSU CHEMICAL CO (JP) 2017-04-05 EP claimed
WO-2003022955-A1 ORGANIC ELECTROLUMINESCENT DEVICE HAVING A POLYIMIDE HOLE TRANSPORT LAYER NESSDISPLAY CO., LTD. (KR) 2003-03-20 WO claimed
US-20020132133-A1 ELECTROLUMINESCENT DEVICE HAVING AN ORGANIC LAYER INCLUDING POLYIMIDE DONGJIN SEMICHEM CO., LTD. (KR) 2002-09-19 US claimed
US-20020098378-A1 Electroluminescent device having an organic layer including polyimide NESS CO., LTD. 2002-07-25 US claimed
US-6342638-B1 Triarylphosphine oxide derivatives containing fluorine substituents KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2002-01-29 US claimed
US-20010005528-A1 Process for the preparation of organic electroluminescent device using vapor deposition polymerization NESSDISPLAY CO., LTD. (KR) 2001-06-28 US claimed
US-20240191028-A1 COMPOSITION FOR MANUFACTURING POLYIMIDE FILM AND POLYIMIDE FILM FOR FLEXIBLE METAL CLAD LAMINATE MANUFACTURED USING THE SAME NEXFLEX CO., LTD. (KR) 2024-06-13 US disclosed
US-20230205031-A1 ELECTROCHROMIC COMPOSITION, ELECTROCHROMIC LAYER AND ELECTROCHROMIC DEVICE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-06-29 US disclosed
US-11624982-B2 Photosensitive resin composition and cured film LG CHEM, LTD. (KR) 2023-04-11 US disclosed
EP-4028448-A1 POLYMER LAYERS BY REACTIVE PRINTING Heraeus Deutschland GmbH & Co. KG (DE) 2022-07-20 EP disclosed
CN-113993931-A Polymers for use in electronic devices 杜邦电子公司 2022-01-28 CN disclosed
EP-0572005-A1 Slipping layer of polyimide-siloxane for dye-donor element used in thermal dye transfer EASTMAN KODAK COMPANY (US) 1993-12-01 EP disclosed
US-5252534-A Slipping layer of polyimide-siloxane for dye-donor element used in thermal dye transfer EASTMAN KODAK COMPANY (US) 1993-10-12 US disclosed
US-5135828-A Triarylamine charge-transport layer in a polyimide binder EASTMAN KODAK COMPANY (US) 1992-08-04 US disclosed
US-5122436-A Homogeneous blend of polyimidesiloxane and unsaturated monomer EASTMAN KODAK COMPANY (US) 1992-06-16 US disclosed
US-5098814-A Integrated circuit chips of laminates of flexible metal strips and photoresists of polyimidesiloxane copolymers EASTMAN KODAK COMPANY (US) 1992-03-24 US disclosed