SCHEMBL4965137

SCHEMBL4965137

Cc1ccc(NCC(C)O)c(C)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.49
MAPT P10636 2/20 0.49
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
HTT P42858 2/20 0.47
VDR P11473 1/20 0.46
ALDH1A1 P00352 3/20 0.45
RAPGEF4 Q8WZA2 1/20 0.44
MAPK1 P28482 3/20 0.43
GAA P10253 2/20 0.43
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12327881 0.85 SMN1; SMN2 (0.47) SMN1; SMN2MAPTKMT2AMEN1HTT
SCHEMBL4853206 0.82 SIGMAR1 (0.46) MAPTHTTVDRALDH1A1
SCHEMBL9435169 0.82 SMN1; SMN2 (0.50) SMN1; SMN2MAPTKMT2AMEN1HTT
SCHEMBL29355470 0.82 ADRB2 (0.47) SMN1; SMN2MAPTKMT2AMEN1HTT
SCHEMBL8360114 0.79 MAPT (0.48) SMN1; SMN2MAPTHTTALDH1A1MAPK1
SCHEMBL11210148 0.78 MAPT (0.52) SMN1; SMN2MAPTKMT2AMEN1HTT
SCHEMBL11211602 0.78 MAPT (0.52) SMN1; SMN2MAPTKMT2AMEN1HTT
SCHEMBL4826263 0.78 MAPT (0.52) SMN1; SMN2MAPTKMT2AMEN1HTT
SCHEMBL11804063 0.77 KMT2A (0.64) SMN1; SMN2KMT2AMEN1HTTALDH1A1
SCHEMBL17006480 0.77 HTT (0.57) MAPTKMT2AMEN1HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4362885-A2 ACRYLIC NAIL ENHANCEMENTS Esschem, Inc. (US) 2024-05-08 EP claimed
WO-2023278269-A2 ACRYLIC NAIL ENHANCEMENTS ESSCHEM, INC. (US) 2023-01-05 WO claimed
EP-0889933-A1 METHODS OF CURING UNSATURATED POLYMERS USING TERTIARY AROMATIC AMINE CURE PROMOTERS First Chemical Corporation (US) 1999-01-13 EP claimed
WO-1997035916-A1 METHODS OF CURING UNSATURATED POLYMERS USING TERTIARY AROMATIC AMINE CURE PROMOTERS FIRST CHEMICAL CORPORATION (US) 1997-10-02 WO claimed
EP-1957573-A1 INITIATOR SYSTEMS FOR USE IN CURING UNSATURATED RESINS, AND CURABLE COMPOSITIONS AND METHODS FOR CURING THEM Albermarle Corporation (US) 2008-08-20 EP disclosed
WO-2007067859-A1 INITIATOR SYSTEMS FOR USE IN CURING UNSATURATED RESINS, AND CURABLE COMPOSITIONS AND METHODS FOR CURING THEM ALBEMARLE CORPORATION (US) 2007-06-14 WO disclosed