Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1733849 | 0.99 | PTPN11 (0.48) | PTGESPTPN11PTPROPLK1FAAH | |
| SCHEMBL4672519 | 0.99 | PTPN11 (0.48) | PTGESPTPN11PTPROPLK1FAAH | |
| SCHEMBL4314702 | 0.99 | PTPN11 (0.48) | PTGESPTPN11PTPROPLK1FAAH | |
| SCHEMBL1853577 | 0.96 | PTGES (0.47) | PTGESPTPN11PTPROPLK1FFAR1 | |
| SCHEMBL1854444 | 0.93 | PTGES (0.48) | PTGESPTPN11PTPROFFAR1PTGDR2 | |
| SCHEMBL1856809 | 0.92 | FAAH (0.51) | PLK1FAAHHDAC1HDAC8ALDH1A1 | |
| SCHEMBL1852821 | 0.91 | PTGES (0.59) | PTGESPTPN11PTPROPLK1FFAR1 | |
| SCHEMBL1853462 | 0.90 | PLK1 (0.50) | PLK1FAAHHDAC1HDAC8ALDH1A1 | |
| SCHEMBL1855895 | 0.90 | PLK1 (0.50) | PLK1FAAHHDAC1HDAC8ALDH1A1 | |
| SCHEMBL4671671 | 0.89 | FFAR1 (0.46) | PTGESPTPN11PTPROPLK1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904048-A1 | GLEPP-1 INHIBITORS IN THE TREATMENT OF AUTOIMMUNE AND/OR INFLAMMATORY DISORDERS | LABORATOIRES SERONO S.A. (CH) | 2008-04-02 | — | — | EP | claimed |
| WO-2007009959-A1 | GLEPP-1 INHIBITORS IN THE TREATMENT OF AUTOIMMUNE AND/OR INFLAMMATORY DISORDERS | LABORATOIRES SERONO S.A. (CH) | 2007-01-25 | — | — | WO | claimed |