SCHEMBL4965590

SCHEMBL4965590

CCCCC1CC(N(Cc2ccccc2)C(=O)Nc2ccccc2)CCN1C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DCUN1D1 Q96GG9 20/20 0.58
UBE2M P61081 19/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2966617 0.82 UBE2M (0.54) DCUN1D1UBE2M
SCHEMBL4965602 0.80 KDM4E (0.43) DCUN1D1UBE2M
SCHEMBL4965596 0.76 DCUN1D1 (0.60) DCUN1D1UBE2M
SCHEMBL18658029 0.73 DCUN1D1 (1.00) DCUN1D1UBE2M
SCHEMBL18657875 0.73 DCUN1D1 (1.00) DCUN1D1UBE2M
SCHEMBL18658086 0.73 DCUN1D1 (0.84) DCUN1D1UBE2M
SCHEMBL18658246 0.73 DCUN1D1 (0.81) DCUN1D1UBE2M
SCHEMBL3049343 0.72 DCUN1D1 (0.60) DCUN1D1UBE2M
SCHEMBL18657676 0.72 DCUN1D1 (1.00) DCUN1D1UBE2M
SCHEMBL18657501 0.72 DCUN1D1 (0.73) DCUN1D1UBE2M

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1960359-A1 NOVEL N-SULFAMOYL-PIPERIDINEAMIDES FOR THE PROPHYLAXIS OR TREATMENT OF OBESITY AND RELATED CONDITIONS Solvay Pharmaceuticals GmbH (DE) 2008-08-27 EP disclosed
WO-2007065948-A1 NOVEL N-SULFAMOYL-PIPERIDINEAMIDES FOR THE PROPHYLAXIS OR TREATMENT OF OBESITY AND RELATED CONDITIONS SOLVAY PHARMACEUTICALS GMBH (DE) 2007-06-14 WO disclosed