Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | UBE2M | P61081 | 7/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4965590 | 0.80 | DCUN1D1 (0.58) | UBE2MDCUN1D1 | |
| SCHEMBL3871317 | 0.71 | HDAC3 (0.39) | CHRM2CHRM3 | |
| SCHEMBL1939688 | 0.69 | FNTA (0.36) | CHRM2CHRM3 | |
| SCHEMBL9905328 | 0.67 | TACR1 (0.54) | — | |
| SCHEMBL6274182 | 0.66 | GNAI3 (0.41) | — | |
| SCHEMBL26090906 | 0.66 | MEN1 (0.44) | KDM4ECHRM2CHRM3OPRM1 | |
| SCHEMBL6418644 | 0.66 | TRPM8 (0.42) | TRPM8UBE2MDCUN1D1 | |
| SCHEMBL3877432 | 0.65 | DPP4 (0.37) | CHRM2CHRM3 | |
| SCHEMBL5067770 | 0.65 | DPP4 (0.35) | CHRM2CHRM3 | |
| SCHEMBL21409263 | 0.63 | CARM1 (0.43) | KDM4ECHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960359-A1 | NOVEL N-SULFAMOYL-PIPERIDINEAMIDES FOR THE PROPHYLAXIS OR TREATMENT OF OBESITY AND RELATED CONDITIONS | Solvay Pharmaceuticals GmbH (DE) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007065948-A1 | NOVEL N-SULFAMOYL-PIPERIDINEAMIDES FOR THE PROPHYLAXIS OR TREATMENT OF OBESITY AND RELATED CONDITIONS | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-06-14 | — | — | WO | disclosed |