Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | CCR2 | P41597 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3479848 | 0.90 | KMT2A (0.50) | KMT2AMEN1PKMCCR2ALDH1A1 | |
| SCHEMBL3479972 | 0.89 | KMT2A (0.52) | KMT2AMEN1PKMCCR2ALDH1A1 | |
| SCHEMBL3479782 | 0.88 | KMT2A (0.51) | KMT2AMEN1PKMCCR2ALDH1A1 | |
| SCHEMBL7146589 | 0.87 | KMT2A (0.50) | KMT2AMEN1PKMCCR2ALDH1A1 | |
| SCHEMBL3479904 | 0.87 | KMT2A (0.53) | KMT2AMEN1PKMCCR2ALDH1A1 | |
| SCHEMBL7147077 | 0.86 | KMT2A (0.49) | KMT2AMEN1PKMCCR2ALDH1A1 | |
| SCHEMBL4965617 | 0.86 | KMT2A (0.49) | KMT2AMEN1PKMCCR2ALDH1A1 | |
| SCHEMBL3479876 | 0.85 | KMT2A (0.51) | KMT2AMEN1PKMCCR2ALDH1A1 | |
| SCHEMBL3479998 | 0.85 | KMT2A (0.50) | KMT2AMEN1PKMCCR2ALDH1A1 | |
| SCHEMBL3480133 | 0.84 | CCR2 (0.51) | KMT2AMEN1PKMCCR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904181-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007011762-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2007-01-25 | — | — | WO | disclosed |