Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18224217 | 0.86 | CTSL (0.53) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL11239042 | 0.86 | CTSL (0.53) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL16485550 | 0.86 | CTSL (0.53) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL31650945 | 0.86 | ACE (0.56) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL7293242 | 0.86 | TACR1 (0.60) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL7293246 | 0.86 | TACR1 (0.60) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL330061 | 0.83 | CTSL (0.55) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL5486969 | 0.83 | CTSL (0.55) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL8976911 | 0.83 | CTSL (0.55) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL23629869 | 0.82 | CTSL (0.58) | CTSLCTSBCTSSCTSKTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804558-B1 | TRIPEPTIDYL AMINOPEPTIDASE | NOVOZYMES AS (DK) | 2008-01-23 | — | — | EP | disclosed |
| WO-1994025581-A1 | MODIFIED RECOMBINANT TISSUE PLASMINOGEN ACTIVATOR | SOUTHERN SYDNEY AREA HEALTH SERVICE (AU) | 1994-11-10 | — | — | WO | disclosed |