SCHEMBL5486969

SCHEMBL5486969

O=C(CNC(=O)OCc1ccccc1)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CTSL P07711 1/20 0.55
CTSB P07858 1/20 0.55
CTSS P25774 1/20 0.55
CTSK P43235 1/20 0.55
ITGB3 P05106 4/20 0.54
ITGA2B P08514 4/20 0.54
TACR1 P25103 2/20 0.53
ALDH1A1 P00352 1/20 0.53
MME P08473 1/20 0.53
ECE1 P42892 1/20 0.53
CTRB1 P17538 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL330061 1.00 CTSL (0.55) CTSLCTSBCTSSCTSKITGB3
SCHEMBL8976911 1.00 CTSL (0.55) CTSLCTSBCTSSCTSKITGB3
SCHEMBL18224217 0.97 CTSL (0.53) CTSLCTSBCTSSCTSKITGB3
SCHEMBL16485550 0.97 CTSL (0.53) CTSLCTSBCTSSCTSKITGB3
SCHEMBL11239042 0.97 CTSL (0.53) CTSLCTSBCTSSCTSKITGB3
SCHEMBL13588070 0.95 MME (0.56) CTSLCTSBCTSSCTSKITGB3
SCHEMBL19065177 0.95 MME (0.56) CTSLCTSBCTSSCTSKITGB3
SCHEMBL27829774 0.95 CTSL (0.57) CTSLCTSBCTSSCTSKTACR1
SCHEMBL8583909 0.94 CTSL (0.53) CTSLCTSBCTSSCTSKITGB3
SCHEMBL8583904 0.93 CTSL (0.49) CTSLCTSBCTSSCTSKITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120189524-A Bispecific antibody-drug conjugate targeting B7H3 and EGFR and application thereof 信达生物制药(苏州)有限公司 2025-06-24 CN claimed
WO-2025092983-A1 B7-H3-TARGETING ANTIBODY-DRUG CONJUGATE AND USE THEREOF 信达生物制药(苏州)有限公司 2025-05-08 WO claimed
CN-119925631-A Antibody-drug conjugate targeting B7-H3 and application thereof 信达生物制药(苏州)有限公司 2025-05-06 CN claimed
CN-119894535-A Oritastatin derivatives and conjugates thereof 祐方有限公司 2025-04-25 CN claimed
WO-2025067306-A1 ANTIBODY-DRUG CONJUGATE TARGETING HER3 信达生物制药(苏州)有限公司 2025-04-03 WO claimed
WO-2025067446-A1 ANTIBODY-DRUG CONJUGATE TARGETING TROP2, AND PREPARATION METHOD AND USE THEREFOR 信达生物制药(苏州)有限公司 2025-04-03 WO claimed
CN-119630672-A Camptothecin derivative and conjugate thereof, and preparation method and medical application thereof 一线医药(杭州)有限公司 2025-03-14 CN claimed
US-20250049938-A1 ANTIBODY-DRUG CONJUGATE AND USE THEREOF SHANGHAI INSTITUTE OF BIOLOGICAL PRODUCTS CO., LTD. (CN) 2025-02-13 US claimed
CN-119119176-A Camptothecin derivatives 伊缪诺金公司 2024-12-13 CN claimed
CN-113766954-B Camptothecin derivatives 伊缪诺金公司 2024-09-24 CN claimed
EP-4431521-A1 ANTIBODY-DRUG CONJUGATE AND USE THEREOF Shanghai Institute of Biological Products Co., Ltd. (CN) 2024-09-18 EP claimed
CN-111051329-B Hamiltelin derivatives and their antibody drug complexes 住友制药株式会社 2024-07-30 CN claimed
WO-2023098691-A1 ANTIBODY-DRUG CONJUGATE AND USE THEREOF 上海生物制品研究所有限责任公司 2023-06-08 WO claimed
CN-116199740-A Antibody drug conjugates and uses thereof 上海生物制品研究所有限责任公司 2023-06-02 CN claimed
CN-115551552-A Camptothecin derivatives and conjugates thereof 祐方有限公司 2022-12-30 CN claimed
US-4415667-A MIXING SWINE-PANCREATIC EXTRACT WITH DUODENUM TO ACTIVATE; PROTEOLYTIC ENZYMES; HYDROLASES EISAI CO., LTD. (JP) 1983-11-15 US claimed
JP-57150384-A None JP disclosed
CN-120189524-A Bispecific antibody-drug conjugate targeting B7H3 and EGFR and application thereof 信达生物制药(苏州)有限公司 2025-06-24 CN disclosed
US-4242507-A Sulfonic acid esters FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-12-30 US disclosed
EP-0010830-A2 Dehydropeptides Research Corporation (US) 1980-05-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250049938-A1 ANTIBODY-DRUG CONJUGATE AND USE THEREOF QPCT, QPCTL, ARGLU1 CTSL 1355/4885CTSB 3046/4885CTSS 3889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.