Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26031976 | 0.94 | — | — | |
| SCHEMBL2995137 | 0.87 | MEN1 (0.31) | — | |
| SCHEMBL7896720 | 0.86 | — | — | |
| SCHEMBL3538324 | 0.84 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL12961665 | 0.78 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL21216739 | 0.76 | — | — | |
| SCHEMBL8148768 | 0.76 | — | — | |
| SCHEMBL14509986 | 0.75 | MEN1 (0.30) | — | |
| SCHEMBL26707517 | 0.73 | EPHX2 (0.36) | ALDH1A1 | |
| SCHEMBL14599332 | 0.73 | EPHX2 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865149-B2 | Polymeric reagents comprising a ketone or a related functional group | NEKTAR THERAPEUTICS (US) | 2014-10-21 | — | — | US | disclosed |
| US-8865149-B2 | Polymeric reagents comprising a ketone or a related functional group | NEKTAR THERAPEUTICS (US) | 2014-10-21 | — | — | US | disclosed |
| US-8835556-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS (US) | 2014-09-16 | — | — | US | disclosed |
| US-20120226022-A1 | HYDROLYTICALLY STABLE MALEIMIDE-TERMINATED POLYMERS | NEKTAR THERAPEUTICS (US) | 2012-09-06 | — | — | US | disclosed |
| US-8227555-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS (US) | 2012-07-24 | — | — | US | disclosed |
| US-20120123065-A1 | Hydrolytically Stable Maleimide-Terminated Polymers | NEKTAR THERAPEUTICS (US) | 2012-05-17 | — | — | US | disclosed |
| US-7432331-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432330-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-20070166277-A1 | Polymeric reagents comprising a ketone or a related functional group | NEKTAR THERAPEUTICS | 2007-07-19 | — | — | US | disclosed |
| US-20070166277-A1 | Polymeric reagents comprising a ketone or a related functional group | NEKTAR THERAPEUTICS | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070166277-A1 | Polymeric reagents comprising a ketone or a related functional group | TKT, KHK, KLK5 | ALDH1A1 422/4885 |
| US-20120226022-A1 | HYDROLYTICALLY STABLE MALEIMIDE-TERMINATED POLYMERS | PADI6, MPI, VIM | ALDH1A1 1089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.