Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.72 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.72 |
| ▸ | CDK2 | P24941 | 10/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.46 |
| ▸ | BRAF | P15056 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 9/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 9/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 9/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 9/20 | 0.43 |
| ▸ | MGMT | P16455 | 4/20 | 0.43 |
| ▸ | PI4KA | P42356 | 2/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoguanine SCHEMBL29569323 | 0.85 | PDPK1 (0.66) | PDPK1GDACDK2DPP4MAP3K5 | |
| Isoguanine SCHEMBL887741 | 0.85 | PDPK1 (0.66) | PDPK1GDACDK2DPP4MAP3K5 | |
| Guanine SCHEMBL122461 | 0.85 | PDPK1 (0.66) | PDPK1GDACDK2DPP4MAP3K5 | |
| 2,6-Diaminopurine SCHEMBL24053 | 0.85 | PDPK1 (1.00) | PDPK1GDACDK2DPP4MAP3K5 | |
| Xanthine SCHEMBL4966 | 0.85 | GDA (0.44) | PDPK1GDACDK2DPP4MAP3K5 | |
| Xanthine SCHEMBL9443819 | 0.85 | GDA (0.44) | PDPK1GDACDK2DPP4MAP3K5 | |
| Xanthine SCHEMBL7044234 | 0.83 | GDA (0.42) | PDPK1GDACDK2DPP4MAP3K5 | |
| 2,6-Diaminopurine SCHEMBL8757979 | 0.83 | PDPK1 (0.96) | PDPK1GDACDK2DPP4MAP3K5 | |
| 2,6-Diaminopurine SCHEMBL27891733 | 0.83 | PDPK1 (0.96) | PDPK1GDACDK2DPP4MAP3K5 | |
| 2,6-Diaminopurine SCHEMBL28206545 | 0.83 | PDPK1 (0.96) | PDPK1GDACDK2DPP4MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696555-B1 | 3'-DEOXYPENTOPYRANOSYLNUCLEOSIDES, OLIGOMERS AND NUCLEIC ACIDS; THERAPEUTIC, DIAGNOSTIC AND/OR ELECTRONIC COMPONENTS | NANOGEN RECOGNOMICS GMBH (DE) | 2004-02-24 | — | — | US | disclosed |