Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1375632 | 0.77 | DAO (0.35) | AURKAAURKBINCENPDAOHDAC8 | |
| SCHEMBL3796424 | 0.72 | — | — | |
| SCHEMBL28399974 | 0.72 | DAO (0.32) | AURKAAURKBINCENPDAOHDAC8 | |
| SCHEMBL2180074 | 0.72 | — | — | |
| SCHEMBL7169327 | 0.69 | TAAR1 (0.32) | AURKAAURKBINCENPDAOHDAC8 | |
| SCHEMBL31568743 | 0.67 | ESR1 (0.33) | — | |
| SCHEMBL5701122 | 0.65 | NR1H2 (0.31) | — | |
| SCHEMBL31722380 | 0.65 | HDAC8 (0.32) | HDAC8HDAC6 | |
| SCHEMBL31722305 | 0.65 | — | — | |
| SCHEMBL19973316 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130047890-A1 | ORGANOMETALLIC COMPOUNDS | PRAXAIR TECHNOLOGY, INC. | 2013-02-28 | — | — | US | claimed |
| WO-2008002415-A2 | PRECURSORS FOR DEPOSITING SILICON CONTAINING FILMS AND PROCESSES THEREOF | PRAXAIR TECHNOLOGY, INC. (US) | 2008-01-03 | — | — | WO | claimed |
| US-20070299274-A1 | Organometallic compounds | PRAXAIR TECHNOLOGY, INC. | 2007-12-27 | — | — | US | claimed |
| US-20130052349-A1 | ORGANOMETALLIC COMPOUNDS | PRAXAIR TECHNOLOGY, INC. | 2013-02-28 | — | — | US | disclosed |
| US-20130047890-A1 | ORGANOMETALLIC COMPOUNDS | PRAXAIR TECHNOLOGY, INC. | 2013-02-28 | — | — | US | disclosed |
| US-8318966-B2 | Organometallic compounds | PRAXAIR TECHNOLOGY, INC. (US) | 2012-11-27 | — | — | US | disclosed |
| WO-2008002415-A2 | PRECURSORS FOR DEPOSITING SILICON CONTAINING FILMS AND PROCESSES THEREOF | PRAXAIR TECHNOLOGY, INC. (US) | 2008-01-03 | — | — | WO | disclosed |
| US-20070299274-A1 | Organometallic compounds | PRAXAIR TECHNOLOGY, INC. | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299274-A1 | Organometallic compounds | NR1H3, NR1H2, NR1I3 | AURKA 3160/4885AURKB 3731/4885INCENP 4023/4885 |
| US-20130052349-A1 | ORGANOMETALLIC COMPOUNDS | NR1H3, NR1H2, NR1I3 | AURKA 3160/4885AURKB 3731/4885INCENP 4023/4885 |
| US-20130047890-A1 | ORGANOMETALLIC COMPOUNDS | NR1H3, NR1H2, NR1I3 | AURKA 3160/4885AURKB 3731/4885INCENP 4023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.