Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.35 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2180074 | 0.77 | — | — | |
| SCHEMBL28399974 | 0.77 | DAO (0.32) | DAOHDAC8HDAC6AURKAAURKB | |
| SCHEMBL4966261 | 0.77 | AURKA (0.37) | DAOHDAC8HDAC6AURKAAURKB | |
| SCHEMBL3796424 | 0.77 | — | — | |
| SCHEMBL7169327 | 0.73 | TAAR1 (0.32) | DAOHDAC8HDAC6AURKAAURKB | |
| SCHEMBL17633740 | 0.71 | ALDH1A1 (0.31) | — | |
| SCHEMBL31568743 | 0.71 | ESR1 (0.33) | — | |
| SCHEMBL5701122 | 0.69 | NR1H2 (0.31) | — | |
| SCHEMBL31722305 | 0.69 | — | — | |
| SCHEMBL31722380 | 0.69 | HDAC8 (0.32) | HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399695-B2 | Organometallic precursor compounds | PRAXAIR TECHNOLOGY, INC. (US) | 2013-03-19 | — | — | US | claimed |
| US-20110293852-A1 | ORGANOMETALLIC PRECURSOR COMPOUNDS | PRAXAIR TECHNOLOGY, INC. | 2011-12-01 | — | — | US | claimed |
| US-7332618-B2 | Organometallic precursor compounds | PRAXAIR TECHNOLOGY, INC. (US) | 2008-02-19 | — | — | US | claimed |
| EP-1805195-A2 | ORGANOMETALLIC PRECURSOR COMPOUNDS | PRAXAIR TECHNOLOGY, INC. (US) | 2007-07-11 | — | — | EP | claimed |
| WO-2006036538-A2 | ORGANOMETALLIC PRECURSOR COMPOUNDS | PRAXAIR TECHNOLOGY, INC. (US) | 2006-04-06 | — | — | WO | claimed |
| US-20060068102-A1 | Organometallic precursor compounds | PRAXAIR TECHNOLOGY, INC. | 2006-03-30 | — | — | US | claimed |
| US-8399695-B2 | Organometallic precursor compounds | PRAXAIR TECHNOLOGY, INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-20110293852-A1 | ORGANOMETALLIC PRECURSOR COMPOUNDS | PRAXAIR TECHNOLOGY, INC. | 2011-12-01 | — | — | US | disclosed |
| US-7332618-B2 | Organometallic precursor compounds | PRAXAIR TECHNOLOGY, INC. (US) | 2008-02-19 | — | — | US | disclosed |
| EP-1805195-A2 | ORGANOMETALLIC PRECURSOR COMPOUNDS | PRAXAIR TECHNOLOGY, INC. (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006036538-A2 | ORGANOMETALLIC PRECURSOR COMPOUNDS | PRAXAIR TECHNOLOGY, INC. (US) | 2006-04-06 | — | — | WO | disclosed |
| US-20060068102-A1 | Organometallic precursor compounds | PRAXAIR TECHNOLOGY, INC. | 2006-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110293852-A1 | ORGANOMETALLIC PRECURSOR COMPOUNDS | MSMO1, NNMT, DNMT1 | DAO 885/4885HDAC8 4059/4885HDAC6 3811/4885 |
| US-20060068102-A1 | Organometallic precursor compounds | MSMO1, NNMT, DNMT1 | DAO 885/4885HDAC8 4059/4885HDAC6 3811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.