Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2354479 | 0.84 | LMNA (0.36) | — | |
| SCHEMBL74076 | 0.84 | — | — | |
| SCHEMBL28286520 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL45666 | 0.81 | — | — | |
| SCHEMBL28293034 | 0.81 | — | — | |
| Hypochlorous Acid SCHEMBL25425590 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL31028436 | 0.77 | — | — | |
| Methyl Alcohol SCHEMBL27933314 | 0.77 | — | — | |
| Carbamic Acid SCHEMBL27083006 | 0.76 | ACHE (0.47) | — | |
| Cyanide SCHEMBL2693274 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008104474-A1 | DIAMINOPYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-09-04 | — | — | WO | disclosed |
| US-20080207655-A1 | Diaminopyrimidines as P2X3 and P2X2/3 modulators | ROCHE PALO ALTO LLC | 2008-08-28 | — | — | US | disclosed |