Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | ACACB | O00763 | 12/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496678 | 1.00 | PPARG (0.47) | PPARGPPARATSHRFFAR1ACACB | |
| SCHEMBL301505 | 0.88 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL495930 | 0.81 | MMP2 (0.49) | TSHR | |
| SCHEMBL495932 | 0.81 | MMP2 (0.49) | TSHR | |
| SCHEMBL495827 | 0.80 | TSHR (0.53) | PPARGPPARATSHRPOLBAPEX1 | |
| SCHEMBL27537093 | 0.80 | TSHR (0.53) | TSHRACACBPOLBAPEX1HTT | |
| SCHEMBL27506485 | 0.77 | TSHR (0.50) | PPARGPPARATSHRFFAR1ACACB | |
| SCHEMBL27502502 | 0.77 | TSHR (0.53) | TSHRACACBPOLBAPEX1HTT | |
| SCHEMBL7766832 | 0.76 | ELANE (0.64) | PPARGPPARAFFAR1ACACBPOLB | |
| SCHEMBL9165741 | 0.75 | HPGD (0.54) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8105662-B2 | Additive components for liquid crystalline materials | ROLIC AG (CH) | 2012-01-31 | — | — | US | disclosed |
| EP-1689827-B1 | ADDITIVE COMPONENTS FOR LIQUID CRYSTALLINE MATERIALS | ROLIC AG (CH) | 2008-07-09 | — | — | EP | disclosed |
| US-20070257230-A1 | Additive Components for Liquid Crystalline Materials | ROLIC AG (CH) | 2007-11-08 | — | — | US | disclosed |
| EP-1689827-A1 | ADDITIVE COMPONENTS FOR LIQUID CRYSTALLINE MATERIALS | Rolic AG (CH) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005054406-A1 | ADDITIVE COMPONENTS FOR LIQUID CRYSTALLINE MATERIALS | ROLIC AG (CH) | 2005-06-16 | — | — | WO | disclosed |