Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 6/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | CA2 | P00918 | 3/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.63 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylhydrochlorothiazide SCHEMBL18314134 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP1A2L3MBTL1LMNACYP3A4 | |
| Paraflutizide SCHEMBL308755 | 0.89 | ALDH1A1 (0.80) | ALDH1A1CYP1A2L3MBTL1LMNACYP3A4 | |
| SCHEMBL18309810 | 0.89 | ALDH1A1 (0.80) | ALDH1A1CYP1A2L3MBTL1LMNACYP3A4 | |
| SCHEMBL18311523 | 0.86 | ALDH1A1 (0.76) | ALDH1A1CYP1A2L3MBTL1LMNACYP3A4 | |
| Hydrobentizide SCHEMBL564232 | 0.86 | ALDH1A1 (0.76) | ALDH1A1CYP1A2L3MBTL1LMNACYP3A4 | |
| Bendroflumethiazide SCHEMBL44537 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CYP1A2L3MBTL1LMNACYP3A4 | |
| Bendroflumethiazide SCHEMBL4427489 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CYP1A2L3MBTL1LMNACYP3A4 | |
| Bendroflumethiazide SCHEMBL3359694 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CYP1A2L3MBTL1LMNACYP3A4 | |
| Bendroflumethiazide SCHEMBL26016 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CYP1A2L3MBTL1LMNACYP3A4 | |
| SCHEMBL13685945 | 0.83 | TDP1 (0.79) | ALDH1A1CYP1A2L3MBTL1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2924 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4722714-A1 | SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) | Korea Institute of Science and Technology (KR) | 2026-04-08 | — | — | EP | claimed |
| CN-118948849-A | Medicine for preventing and treating diseases related to anti-obesity effect | 盐野义制药株式会社 | 2024-11-15 | — | — | CN | claimed |
| US-20240374587-A1 | MEDICINE FOR PREVENTION AND TREATMENT OF DISEASES LINKED TO ANTI-OBESITY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2024-11-14 | — | — | US | claimed |
| EP-4400105-A1 | MEDICINE FOR PREVENTION AND TREATMENT OF DISEASES LINKED TO ANTI-OBESITY ACTIVITY | Shionogi & Co., Ltd (JP) | 2024-07-17 | — | — | EP | claimed |
| EP-3025711-B1 | MEDICINE FOR PREVENTING OR TREATING HYPERTENSION | DAIICHI SANKYO CO LTD (JP) | 2020-11-18 | — | — | EP | claimed |
| US-20180118773-A1 | CRYSTALLINE FORM OF BENZYLBENZENE SGLT2 INHIBITOR | THERACOSBIO, LLC | 2018-05-03 | — | — | US | claimed |
| US-20160206593-A1 | PHARMACEUTICAL FOR PROPHYLAXIS OR TREATMENT OF HYPERTENSION | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-07-21 | — | — | US | claimed |
| EP-3025711-A1 | MEDICINE FOR PREVENTING OR TREATING HYPERTENSION | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-06-01 | — | — | EP | claimed |
| US-20160058874-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | CERULEAN PHARMA INC. (US) | 2016-03-03 | — | — | US | claimed |
| US-20160008328-A1 | Stable Pharmaceutical Package Comprising Azilsartan Medoxomil | CADILA HEALTHCARE LIMITED (IN) | 2016-01-14 | — | — | US | claimed |
| EP-1354602-A1 | MEDICINAL COMPOSITIONS CONTAINING DIURETIC AND INSULIN RESISTANCE-IMPROVING AGENT | Sankyo Company, Limited (JP) | 2003-10-22 | — | — | EP | claimed |
| US-20030162824-A1 | Methods of treating or preventing a cardiovascular condition using a cyclooxygenase-1 inhibitor | PHARMACIA CORPORATION | 2003-08-28 | — | — | US | claimed |
| EP-1336407-A1 | MEDICINAL COMPOSITIONS | Sankyo Company, Limited (JP) | 2003-08-20 | — | — | EP | claimed |
| CN-1315945-A | Nitrate salts of antihypertensive drugs | NICOX SA (FR) | 2001-10-03 | — | — | CN | claimed |
| CN-1294519-A | Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient | INPHARMA SA (CH) | 2001-05-09 | — | — | CN | claimed |
| EP-1087953-A1 | NITRATE SALTS OF ANTIHYPERTENSIVE MEDICINES | NICOX S.A. (FR) | 2001-04-04 | — | — | EP | claimed |
| EP-1073470-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2001-02-07 | — | — | EP | claimed |
| WO-2000048636-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2000-08-24 | — | — | WO | claimed |
| WO-1999067231-A1 | NITRATE SALTS OF ANTIHYPERTENSIVE MEDICINES | NICOX S.A. (FR) | 1999-12-29 | — | — | WO | claimed |
| US-5811547-A | Method for inducing crystalline state transition in medicinal substance | NIPPON SHINYAJU CO., LTD. (JP) | 1998-09-22 | — | — | US | claimed |