Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 6/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | CA2 | P00918 | 3/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.63 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylhydrochlorothiazide SCHEMBL49671 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP1A2L3MBTL1LMNACYP3A4 | |
| Paraflutizide SCHEMBL308755 | 0.89 | ALDH1A1 (0.80) | ALDH1A1CYP1A2L3MBTL1LMNACYP3A4 | |
| SCHEMBL18309810 | 0.89 | ALDH1A1 (0.80) | ALDH1A1CYP1A2L3MBTL1LMNACYP3A4 | |
| SCHEMBL18311523 | 0.86 | ALDH1A1 (0.76) | ALDH1A1CYP1A2L3MBTL1LMNACYP3A4 | |
| Hydrobentizide SCHEMBL564232 | 0.86 | ALDH1A1 (0.76) | ALDH1A1CYP1A2L3MBTL1LMNACYP3A4 | |
| Bendroflumethiazide SCHEMBL44537 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CYP1A2L3MBTL1LMNACYP3A4 | |
| Bendroflumethiazide SCHEMBL4427489 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CYP1A2L3MBTL1LMNACYP3A4 | |
| Bendroflumethiazide SCHEMBL3359694 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CYP1A2L3MBTL1LMNACYP3A4 | |
| Bendroflumethiazide SCHEMBL26016 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CYP1A2L3MBTL1LMNACYP3A4 | |
| SCHEMBL13685945 | 0.83 | TDP1 (0.79) | ALDH1A1CYP1A2L3MBTL1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160361298-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | GLOBAVIR BIOSCIENCES, INC. | 2016-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160361298-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | IDO2, IDO1, TDO2 | ALDH1A1 977/4885CYP1A2 2188/4885L3MBTL1 3566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.