Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.64 |
| ▸ | HTR1D | P28221 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3139127 | 0.87 | HTR6 (0.66) | HTR6HTR1DHTR1AHTR1BMPO | |
| SCHEMBL3139135 | 0.87 | HTR6 (0.66) | HTR6HTR1DHTR1AHTR1BMPO | |
| SCHEMBL30464849 | 0.87 | HTR6 (0.66) | HTR6HTR1DHTR1AHTR1BMPO | |
| SCHEMBL4970689 | 0.81 | HTR6 (0.83) | HTR6HTR1DHTR1AHTR1BMPO | |
| Biphenyl SCHEMBL4969876 | 0.79 | HTR6 (0.78) | HTR6HTR1DHTR1AHTR1BMPO | |
| SCHEMBL4966738 | 0.78 | HTR6 (0.75) | HTR6HTR1DHTR1AHTR1BMPO | |
| SCHEMBL4970421 | 0.78 | HTR6 (0.50) | HTR6HTR1DHTR1AHTR1BMPO | |
| SCHEMBL3144603 | 0.78 | HTR6 (1.00) | HTR6HTR1DHTR1AHTR1BMPO | |
| SCHEMBL3323841 | 0.77 | HTR6 (0.74) | HTR6HTR1DHTR1AHTR1BMPO | |
| SCHEMBL4970351 | 0.76 | HTR6 (0.84) | HTR6HTR1DHTR1AHTR1BMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626715-B1 | USE OF SULPHONAMIDE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE PROPHYLAXIS AND/OR TREATMENT OF DISORDERS OF FOOD INGESTION | ESTEVE LABOR DR (ES) | 2008-09-10 | — | — | EP | claimed |