Sugi Predict

Sugi Predict / Compounds / Biphenyl

Biphenyl

Biphenyl

SCHEMBL4969876

CCN(CC)CCc1c[nH]c2ccc(NS(N)(=O)=O)cc12.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ HTR6 P50406 13/20 0.78
▸ HTR1A P08908 3/20 0.56
▸ HTR1D P28221 3/20 0.53
▸ HTR1B P28222 1/20 0.53
▸ MPO P05164 1/20 0.52
▸ HTR2A P28223 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL4968488 0.89 HTR6 (0.77) HTR6HTR1AHTR1DHTR1BMPO
SCHEMBL3144603 0.88 HTR6 (1.00) HTR6HTR1AHTR1DHTR1BMPO
SCHEMBL4970296 0.88 HTR6 (0.72) HTR6HTR1AHTR1DHTR1BMPO
SCHEMBL1576005 0.82 HTR6 (0.85) HTR6HTR1A
SCHEMBL4970689 0.81 HTR6 (0.83) HTR6HTR1AHTR1DHTR1BMPO
SCHEMBL3139135 0.81 HTR6 (0.66) HTR6HTR1AHTR1DHTR1BMPO
SCHEMBL30464849 0.81 HTR6 (0.66) HTR6HTR1AHTR1DHTR1BMPO
SCHEMBL3139127 0.81 HTR6 (0.66) HTR6HTR1AHTR1DHTR1BMPO
Diphenylether SCHEMBL4967821 0.80 HTR6 (0.64) HTR6HTR1AHTR1DHTR1BMPO
SCHEMBL4967323 0.79 HTR6 (0.64) HTR6HTR1AHTR1DHTR1BMPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1626715-B1 USE OF SULPHONAMIDE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE PROPHYLAXIS AND/OR TREATMENT OF DISORDERS OF FOOD INGESTION ESTEVE LABOR DR (ES) 2008-09-10 — — EP claimed