Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104892 | 0.87 | HSD17B10 (0.44) | HSD17B10ANPEPERAP2RAD52MEN1 | |
| SCHEMBL28366615 | 0.75 | HSD17B10 (0.49) | HSD17B10ANPEPERAP2RAD52MEN1 | |
| SCHEMBL8095289 | 0.73 | CARM1 (0.36) | ALDH1A1KDM1AL3MBTL1ACE2TSHR | |
| SCHEMBL13185218 | 0.72 | RAD52 (0.50) | HSD17B10ANPEPERAP2RAD52MEN1 | |
| SCHEMBL28670801 | 0.72 | CHRM5 (0.31) | MEN1KMT2ACHRM5CHRM3 | |
| SCHEMBL2463406 | 0.70 | ANPEP (0.42) | HSD17B10ANPEPERAP2RAD52MEN1 | |
| SCHEMBL14500287 | 0.69 | HSD17B10 (0.50) | HSD17B10ANPEPERAP2RAD52MEN1 | |
| SCHEMBL28879363 | 0.69 | MEN1 (0.52) | HSD17B10ANPEPERAP2RAD52MEN1 | |
| SCHEMBL14500286 | 0.69 | HSD17B10 (0.53) | HSD17B10ANPEPERAP2RAD52MEN1 | |
| SCHEMBL302850 | 0.68 | ACE2 (0.72) | HSD17B10ANPEPERAP2RAD52MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1962851-A2 | COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007076320-A2 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |