Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 5/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4968100 | 1.00 | BRD4 (0.37) | BRD4KAT2BSIRT2KDM4EALDH1A1 | |
| SCHEMBL4970577 | 1.00 | BRD4 (0.37) | BRD4KAT2BSIRT2KDM4EALDH1A1 | |
| SCHEMBL4969216 | 0.90 | SIRT2 (0.38) | BRD4KAT2BSIRT2MAPTL3MBTL1 | |
| SCHEMBL4969213 | 0.90 | SIRT2 (0.38) | BRD4KAT2BSIRT2MAPTL3MBTL1 | |
| SCHEMBL4969540 | 0.90 | SIRT2 (0.38) | BRD4KAT2BSIRT2MAPTL3MBTL1 | |
| SCHEMBL4967526 | 0.90 | CYP3A4 (0.37) | BRD4KAT2BKDM4EALDH1A1 | |
| SCHEMBL4967521 | 0.90 | CYP3A4 (0.37) | BRD4KAT2BKDM4EALDH1A1 | |
| SCHEMBL4969672 | 0.90 | CYP3A4 (0.37) | BRD4KAT2BKDM4EALDH1A1 | |
| SCHEMBL4970715 | 0.88 | KMO (0.40) | BRD4KDM4E | |
| SCHEMBL4968263 | 0.88 | KMO (0.40) | BRD4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985297-A1 | CARBOXYLIC ACID COMPOUND AND USE THEREOF | Japan Tobacco, Inc. (JP) | 2008-10-29 | — | — | EP | disclosed |
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | JAPAN TOBACCO INC. (JP) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | GLS, SLC10A1, SOAT1 | BRD4 3303/4885KAT2B 1512/4885SIRT2 2057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.