Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4967785 | 0.88 | PDE4A (0.41) | MEN1KMT2ANPSR1PDE4AMAPT | |
| SCHEMBL4968649 | 0.86 | PDE4D (0.38) | PDE4ASLC5A1SLC5A2 | |
| SCHEMBL4967734 | 0.86 | PDE4D (0.38) | PDE4ASLC5A1SLC5A2 | |
| SCHEMBL4967723 | 0.86 | PDE4D (0.38) | PDE4ASLC5A1SLC5A2 | |
| SCHEMBL4969143 | 0.81 | POLB (0.36) | POLBCSNK2A1MEN1KMT2ANPSR1 | |
| SCHEMBL1252319 | 0.81 | ALDH1A1 (0.44) | POLBMAPTALDH1A1GAA | |
| SCHEMBL14116545 | 0.80 | MAPT (0.39) | POLBMEN1KMT2AMAPTLMNA | |
| SCHEMBL4968269 | 0.78 | RORC (0.38) | POLBMEN1KMT2ANPSR1IKBKB | |
| SCHEMBL4966698 | 0.77 | CSNK2A1 (0.36) | POLBCSNK2A1MEN1KMT2AALDH1A1 | |
| SCHEMBL4966210 | 0.77 | KMT2A (0.41) | POLBCSNK2A1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008101938-A1 | GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZONITRILE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-28 | — | — | WO | disclosed |
| WO-2008101938-A1 | GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZONITRILE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-28 | — | — | WO | disclosed |