Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8379654 | 0.81 | ALDH1A1 (0.39) | TSHRTDP1 | |
| SCHEMBL14582993 | 0.81 | BTN3A1 (0.38) | — | |
| SCHEMBL1476871 | 0.78 | LMNA (0.37) | TSHRTDP1 | |
| SCHEMBL8096461 | 0.76 | FFAR3 (0.40) | TSHRTDP1 | |
| SCHEMBL261411 | 0.76 | FFAR3 (0.40) | TSHRTDP1 | |
| SCHEMBL11551308 | 0.76 | — | — | |
| SCHEMBL10888746 | 0.75 | LMNA (0.32) | TSHR | |
| SCHEMBL21174460 | 0.75 | — | — | |
| SCHEMBL19821938 | 0.74 | KDM4E (0.32) | — | |
| SCHEMBL1376978 | 0.74 | LMNA (0.48) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312206-A1 | Chemical Compounds-149 | ASTRAZENECA AB (SE) | 2008-12-18 | — | — | US | disclosed |
| EP-1966174-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007071955-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312206-A1 | Chemical Compounds-149 | CSF3R, CSF1R, FLT3 | TSHR 2649/4885TDP1 4065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.