Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 5/20 | 0.45 |
| ▸ | MME | P08473 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969760 | 0.87 | MEN1 (0.56) | SMN1; SMN2TSHRL3MBTL1MAPK1ACE | |
| SCHEMBL4968281 | 0.86 | LMNA (0.52) | SMN1; SMN2TSHRL3MBTL1MAPK1 | |
| SCHEMBL10359084 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2TSHRL3MBTL1MAPK1ACE | |
| SCHEMBL10506983 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHRL3MBTL1MAPK1ACE | |
| SCHEMBL4968814 | 0.79 | MEN1 (0.48) | SMN1; SMN2TSHRL3MBTL1MAPK1 | |
| SCHEMBL4469966 | 0.78 | POLB (0.55) | SMN1; SMN2TSHRL3MBTL1MAPK1 | |
| SCHEMBL10509805 | 0.78 | ACE (0.47) | SMN1; SMN2TSHRL3MBTL1ACEMME | |
| SCHEMBL10358569 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHRL3MBTL1MAPK1ACE | |
| SCHEMBL3251959 | 0.75 | SMN1; SMN2 (0.53) | SMN1; SMN2TSHRL3MBTL1MAPK1 | |
| SCHEMBL19585131 | 0.74 | KDM4E (0.51) | SMN1; SMN2TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985297-A1 | CARBOXYLIC ACID COMPOUND AND USE THEREOF | Japan Tobacco, Inc. (JP) | 2008-10-29 | — | — | EP | claimed |
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | JAPAN TOBACCO INC. (JP) | 2007-08-23 | — | — | US | claimed |
| EP-1985297-A1 | CARBOXYLIC ACID COMPOUND AND USE THEREOF | Japan Tobacco, Inc. (JP) | 2008-10-29 | — | — | EP | disclosed |
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | JAPAN TOBACCO INC. (JP) | 2007-08-23 | — | — | US | disclosed |
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | JAPAN TOBACCO INC. (JP) | 2007-08-23 | — | — | US | disclosed |
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | JAPAN TOBACCO INC. (JP) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | GLS, SLC10A1, SOAT1 | SMN1; SMN2 4151/4885TSHR 4003/4885L3MBTL1 466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.