Sugi Predict

Sugi Predict / Compounds / Biphenyl

Biphenyl

Biphenyl

SCHEMBL4968404

NS(=O)(=O)Nc1ccc2[nH]cc(CCN3CCOCC3)c2c1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ HTR6 P50406 11/20 0.67
▸ HRH3 Q9Y5N1 2/20 0.47
▸ HTR7 P34969 2/20 0.47
▸ HTR2A P28223 1/20 0.46
▸ HTR1A P08908 1/20 0.45
▸ HTR1D P28221 2/20 0.45
▸ HTR1B P28222 2/20 0.45
▸ DRD2 P14416 1/20 0.44
▸ DRD1 P21728 1/20 0.44
▸ DRD4 P21917 1/20 0.44
▸ DRD5 P21918 1/20 0.44
▸ DRD3 P35462 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3142976 0.89 HTR6 (0.79) HTR6
SCHEMBL5656829 0.85 HTR6 (0.76) HTR6HTR7HTR2AHTR1AHTR1D
SCHEMBL4968803 0.83 HTR6 (0.84) HTR6HRH3HTR7HTR1DHTR1B
SCHEMBL3153146 0.80 HTR6 (1.00) HTR6HTR7HTR2AHTR1AHTR1D
SCHEMBL3147744 0.80 HTR6 (1.00) HTR6
SCHEMBL4969882 0.80 HTR6 (0.76) HTR6HRH3HTR7HTR2AHTR1D
Biphenyl SCHEMBL4968488 0.78 HTR6 (0.77) HTR6HTR7HTR2AHTR1AHTR1D
SCHEMBL3156785 0.77 HTR6 (0.79) HTR6
SCHEMBL29992486 0.76 HTR2A (0.76) HTR6HRH3HTR2AHTR1ADRD2
SCHEMBL734052 0.76 HTR2A (0.76) HTR6HRH3HTR2AHTR1ADRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1626715-B1 USE OF SULPHONAMIDE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE PROPHYLAXIS AND/OR TREATMENT OF DISORDERS OF FOOD INGESTION ESTEVE LABOR DR (ES) 2008-09-10 — — EP claimed