Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 17/20 | 0.76 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR1F | P30939 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3142976 | 0.87 | HTR6 (0.79) | HTR6 | |
| SCHEMBL3153146 | 0.86 | HTR6 (1.00) | HTR6HTR1AHTR7HTR1DHTR1B | |
| Biphenyl SCHEMBL4968404 | 0.85 | HTR6 (0.67) | HTR6HTR1AHTR7HTR1DHTR1B | |
| SCHEMBL3156785 | 0.82 | HTR6 (0.79) | HTR6 | |
| SCHEMBL3147744 | 0.81 | HTR6 (1.00) | HTR6 | |
| SCHEMBL4968803 | 0.80 | HTR6 (0.84) | HTR6HTR7HTR1DHTR1B | |
| SCHEMBL3147704 | 0.78 | HTR6 (1.00) | HTR6HTR1AHTR7HTR1DHTR1B | |
| SCHEMBL4969882 | 0.77 | HTR6 (0.76) | HTR6HTR7HTR1DHTR1BHTR2A | |
| SCHEMBL3153502 | 0.73 | HTR6 (0.69) | HTR6HTR1AHTR7HTR1DHTR1B | |
| SCHEMBL4966642 | 0.72 | HTR6 (0.64) | HTR6HTR7HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176200-B2 | Derivatives of sulphonamides, their preparation and use as medicaments | LABORATORIES DEL DR. ESTEVE, S.A. (ES) | 2007-02-13 | — | — | US | claimed |