Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | MARK3 | P27448 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | FRK | P42685 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.41 |
| ▸ | STK3 | Q13188 | 1/20 | 0.41 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24352377 | 0.82 | AR (0.40) | ARLMNAPFKFB3HDAC1HDAC6 | |
| SCHEMBL2331355 | 0.80 | TRPV4 (0.41) | SLC40A1KDM4ERAB9AP2RX7PTGS2 | |
| SCHEMBL3462719 | 0.80 | AURKA (0.41) | SRPK1GSK3AGSK3BLMNASLC40A1 | |
| SCHEMBL18463777 | 0.79 | AR (0.38) | ARLMNAPFKFB3HDAC1HDAC6 | |
| SCHEMBL7253959 | 0.78 | METAP2 (0.53) | PIM1LMNASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL28507492 | 0.78 | MAPT (0.45) | SLC40A1KDM4EP2RX7MAPTTDP1 | |
| SCHEMBL29496084 | 0.78 | BACE1 (0.53) | ARLMNASLC40A1SMN1; SMN2NPC1 | |
| SCHEMBL8325687 | 0.78 | ELANE (0.41) | ARLMNAPFKFB3SLC40A1PTGS2 | |
| SCHEMBL30586432 | 0.78 | ELANE (0.41) | ARLMNAPFKFB3SLC40A1PTGS2 | |
| SCHEMBL30586451 | 0.78 | MAP4K4 (0.42) | MAP4K4CDK2MAPKAPK2RPS6KA3CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115466212-B | 2-trifluoromethyl quinoline compound and synthetic method and application thereof | 河南农业大学 | 2023-09-22 | — | — | CN | disclosed |
| EP-1968968-A1 | COMPOSITIONS AND METHODS FOR MODULATING GATED ION CHANNELS | PainCeptor Pharma Corp. (CA) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007071055-A1 | COMPOSITIONS AND METHODS FOR MODULATING GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-06-28 | — | — | WO | disclosed |
| US-4009020-A | QUINOLINE-4-CARBOXYLIC ACID OR SALTS | AMCHEM PRODUCTS, INC. (US) | 1977-02-22 | — | — | US | disclosed |