Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738792 | 0.97 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL1091612 | 0.92 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL1090984 | 0.86 | — | — | |
| SCHEMBL28959862 | 0.80 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL2864827 | 0.80 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL23995726 | 0.77 | — | — | |
| SCHEMBL10202610 | 0.75 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL23344997 | 0.75 | — | — | |
| SCHEMBL11272259 | 0.75 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL9682850 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11648254-B2 | Substituted pyrido[2,3-d]pyrimidines as inhibitors of Ras pathway signaling | KUMQUAT BIOSCIENCES INC. (US) | 2023-05-16 | — | — | US | disclosed |
| US-20210214389-A1 | DIASTEREOMERIC CONJUGATE COMPOSITIONS AND METHODS OF MAKING AND USING SAME | OSTEOANALGESIA, LLC | 2021-07-15 | — | — | US | disclosed |
| US-9938236-B2 | Antiviral agents against HBV infection | DREXEL UNIVERSITY (US) | 2018-04-10 | — | — | US | disclosed |
| US-9938236-B2 | Antiviral agents against HBV infection | DREXEL UNIVERSITY (US) | 2018-04-10 | — | — | US | disclosed |
| US-20160024004-A1 | NOVEL ANTIVIRAL AGENTS AGAINST HBV INFECTION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-28 | — | — | US | disclosed |
| JP-2008150376-A | NEW METHOD FOR SYNTHESIZING [R-(R*,R*)]-2-(4-FLUOROPHENYL)-β, δ-DIHYDROXY-5-(1-METHYLETHYL)-3-PHENYL-4-[(PHENYLAMINO)CARBONYL]-1H-PYRROLE-1-HEPTANOIC ACID OR ITS PHARMACEUTICALLY ACCEPTABLE SALT | PFIZER PROD INC | 2008-07-03 | — | — | JP | disclosed |
| EP-0210760-B1 | METHOD FOR THE PREPARATION OF CROSS-LINKED POLYETHYLENE FOAMS AND FOAMS PRODUCED BY THE METHOD | BP CHEMICALS FOAMS BUSINESS, SA (ES) | 1992-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11648254-B2 | Substituted pyrido[2,3-d]pyrimidines as inhibitors of Ras pathway signaling | KRAS, NRAS, BRAF | ALDH1A1 1973/4885GAA 4392/4885PDE4A 1717/4885 |
| US-20160024004-A1 | NOVEL ANTIVIRAL AGENTS AGAINST HBV INFECTION | HAVCR2, EIF2AK2, NR1H4 | ALDH1A1 2569/4885GAA 1127/4885PDE4A 2596/4885 |
| US-20210214389-A1 | DIASTEREOMERIC CONJUGATE COMPOSITIONS AND METHODS OF MAKING AND USING SAME | NR3C1, GCG, NR3C2 | ALDH1A1 1328/4885GAA 2008/4885PDE4A 721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.