Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4968940 | 1.00 | ALDH1A1 (0.42) | ALDH1A1CREBBPDGAT1MAPTSMN1; SMN2 | |
| SCHEMBL4969791 | 0.92 | ALDH1A1 (0.45) | ALDH1A1MAPTSMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL4969782 | 0.92 | ALDH1A1 (0.45) | ALDH1A1MAPTSMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL4969005 | 0.90 | POLB (0.42) | ALDH1A1DGAT1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL4969002 | 0.90 | POLB (0.42) | ALDH1A1DGAT1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL4970363 | 0.87 | CREBBP (0.46) | ALDH1A1CREBBPDGAT1MAPTSMN1; SMN2 | |
| SCHEMBL4970370 | 0.87 | CREBBP (0.46) | ALDH1A1CREBBPDGAT1MAPTSMN1; SMN2 | |
| SCHEMBL4971285 | 0.83 | POLB (0.47) | ALDH1A1MAPTMEN1KMT2ATP53 | |
| SCHEMBL4971276 | 0.83 | POLB (0.47) | ALDH1A1MAPTMEN1KMT2ATP53 | |
| SCHEMBL4970020 | 0.81 | ALDH1A1 (0.46) | ALDH1A1CREBBPMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985297-A1 | CARBOXYLIC ACID COMPOUND AND USE THEREOF | Japan Tobacco, Inc. (JP) | 2008-10-29 | — | — | EP | disclosed |
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | JAPAN TOBACCO INC. (JP) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | GLS, SLC10A1, SOAT1 | ALDH1A1 142/4885CREBBP 2067/4885DGAT1 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.