Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 6/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 5/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969066 | 0.81 | CA2 (0.54) | CA2GSK3BBRD4CREBBPPARP1 | |
| SCHEMBL22822780 | 0.80 | PARP1 (0.53) | BRD4CREBBPPARP1TRPV1BRPF1 | |
| SCHEMBL4968919 | 0.79 | CA2 (0.51) | CA2GSK3BBRD4CREBBPPARP1 | |
| SCHEMBL4969956 | 0.78 | CA2 (0.54) | CA2GSK3BBRD4CREBBPPARP1 | |
| SCHEMBL21695777 | 0.78 | CA2 (0.54) | CA2GSK3BBRD4CREBBPPARP1 | |
| SCHEMBL4972202 | 0.78 | CA2 (0.50) | CA2GSK3BBRD4CREBBPPARP1 | |
| SCHEMBL5118106 | 0.76 | CA2 (0.51) | CA2GSK3BBRD4CREBBPPARP1 | |
| SCHEMBL4968933 | 0.76 | BRD4 (0.37) | CA2BRD4CREBBPPARP1HPGD | |
| SCHEMBL17634184 | 0.75 | CA2 (0.37) | CA2GSK3BBRD4PARP1ALDH1A1 | |
| SCHEMBL5670399 | 0.72 | CA2 (0.62) | CA2GSK3BBRD4CREBBPPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985297-A1 | CARBOXYLIC ACID COMPOUND AND USE THEREOF | Japan Tobacco, Inc. (JP) | 2008-10-29 | — | — | EP | disclosed |
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | JAPAN TOBACCO INC. (JP) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | GLS, SLC10A1, SOAT1 | CA2 363/4885GSK3B 3902/4885BRD4 3303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.