Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.38 |
| ▸ | ACE | P12821 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4973945 | 0.96 | RAB9A (0.40) | RAB9ABRD4TSHRALDH1A1KDM4E | |
| SCHEMBL4972397 | 0.93 | MME (0.40) | MMEACERAB9ABRD4MEN1 | |
| SCHEMBL4973363 | 0.90 | RAB9A (0.39) | RAB9ABRD4TSHRALDH1A1KDM4E | |
| SCHEMBL4968254 | 0.86 | CDC25A (0.38) | MMEACEBRD4ALDH1A1MEN1 | |
| SCHEMBL4970662 | 0.85 | MEN1 (0.41) | RAB9ABRD4TSHRALDH1A1MEN1 | |
| SCHEMBL10358621 | 0.85 | MEN1 (0.41) | RAB9ABRD4TSHRALDH1A1MEN1 | |
| SCHEMBL4972236 | 0.85 | RAB9A (0.38) | RAB9AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4968981 | 0.84 | ALDH1A1 (0.39) | BRD4TSHRALDH1A1KDM4EMEN1 | |
| SCHEMBL4969728 | 0.84 | KMT2A (0.39) | RAB9ABRD4TSHRALDH1A1KDM4E | |
| SCHEMBL4970216 | 0.83 | ALDH1A1 (0.40) | BRD4TSHRALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985297-A1 | CARBOXYLIC ACID COMPOUND AND USE THEREOF | Japan Tobacco, Inc. (JP) | 2008-10-29 | — | — | EP | disclosed |