Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRD1 | O95696 | 1/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4966244 | 0.87 | NR1I2 (0.49) | LMNAMEN1KMT2AMAPTNR1I2 | |
| SCHEMBL8927745 | 0.77 | SLC2A1 (0.43) | LMNAALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL4966071 | 0.73 | CNR2 (0.64) | HPGD | |
| SCHEMBL4965990 | 0.71 | CNR2 (0.68) | SMN1; SMN2 | |
| SCHEMBL4965771 | 0.71 | CNR2 (0.72) | SMN1; SMN2LMNA | |
| SCHEMBL4966045 | 0.71 | CNR2 (0.61) | F2HPGDSMN1; SMN2PAX8POLB | |
| SCHEMBL4968467 | 0.70 | CNR2 (0.60) | F2HPGDSMN1; SMN2PAX8POLB | |
| SCHEMBL4966119 | 0.69 | CNR2 (0.65) | F2HPGDSMN1; SMN2PAX8POLB | |
| SCHEMBL4966392 | 0.69 | CNR2 (0.66) | — | |
| SCHEMBL14115753 | 0.69 | F2 (0.54) | F2HPGDSMN1; SMN2PAX8POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670790-B1 | BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF | ASTRAZENECA AB (SE) | 2008-08-20 | — | — | EP | claimed |