Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969422 | 0.77 | F2 (0.50) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4966244 | 0.72 | NR1I2 (0.49) | CYP2C9CYP1A2CYP2C19CYP2D6MEN1 | |
| SCHEMBL6171933 | 0.72 | PPARG (0.54) | MEN1KMT2APPARGMAPT | |
| SCHEMBL9195588 | 0.71 | NLRP3 (0.55) | KDM4ENLRP3MEN1KMT2AALDH1A1 | |
| SCHEMBL9048541 | 0.69 | CYP19A1 (0.46) | KDM4ECYP2C9CYP1A2CYP2C19MEN1 | |
| SCHEMBL2242774 | 0.69 | NLRP3 (0.60) | KDM4ENLRP3CYP1A2MEN1KMT2A | |
| SCHEMBL6171555 | 0.68 | PPARG (0.55) | CYP2C9CYP1A2CYP2C19CYP2D6MEN1 | |
| SCHEMBL9046935 | 0.68 | CYP1A2 (0.52) | KDM4ECYP2C9CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL25878191 | 0.67 | ALDH1A1 (0.44) | KDM4EALDH1A1TSHR | |
| SCHEMBL16904967 | 0.67 | TRPC5 (0.51) | NLRP3CYP2C9CYP1A2CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656649-A | PESTICIDE, INSECTICIDES, NEMATOCIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-12 | — | — | US | disclosed |
| US-5482956-A | ANTIPROTOZOA AGENTS FOR ANIMALS OR INSECTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-09 | — | — | US | disclosed |
| WO-1994011349-A1 | 2-FLUOROALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-26 | — | — | WO | disclosed |
| EP-0597304-A1 | Use of substituted benzimidazoles | BAYER AG (DE) | 1994-05-18 | — | — | EP | disclosed |