SCHEMBL4969625

SCHEMBL4969625

Cc1cc(C)c(N=CCc2cccc(Br)n2)c(Cl)c1

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.30
MAPT P10636 2/20 0.30
KMT2A Q03164 2/20 0.30
PLA2G1B P04054 1/20 0.30
ATG4B Q9Y4P1 1/20 0.30
ACKR3 P25106 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16653951 0.91 NOS1 (0.35)
SCHEMBL14830125 0.90 NOS1 (0.34)
SCHEMBL23535362 0.90 NOS1 (0.34)
Hydrochloric Acid SCHEMBL3671010 0.88 NOS1 (0.33)
SCHEMBL20703459 0.87 NOS1 (0.35)
SCHEMBL25439645 0.87 NOS1 (0.33)
SCHEMBL4968598 0.85 NOS1 (0.31) MEN1MAPTKMT2A
SCHEMBL4970674 0.84 RAPGEF4 (0.34) MAPT
SCHEMBL4968681 0.81 MRGPRX4 (0.35) MEN1KMT2A
SCHEMBL812525 0.81 NOS1 (0.39) MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1973879-A2 PROCESS FOR PREPARING IMINO COMPOUNDS Basell Polyolefine GmbH (DE) 2008-10-01 EP disclosed
WO-2007080121-A2 PROCESS FOR PREPARING IMINO COMPOUNDS BASELL POLYOLEFINE GMBH (DE) 2007-07-19 WO disclosed