Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 10/20 | 0.45 |
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4973950 | 1.00 | REN (0.45) | RENCFDKDM4EALDH1A1TSHR | |
| SCHEMBL4973471 | 0.91 | REN (0.43) | RENKDM4E | |
| SCHEMBL4971018 | 0.90 | REN (0.46) | RENCFDKDM4EALDH1A1TSHR | |
| SCHEMBL4971183 | 0.85 | REN (0.45) | RENCFDKDM4EALDH1A1TSHR | |
| SCHEMBL1862352 | 0.82 | REN (0.53) | RENTSHR | |
| SCHEMBL1861478 | 0.82 | REN (0.53) | RENTSHR | |
| SCHEMBL1862351 | 0.82 | REN (0.53) | RENTSHR | |
| SCHEMBL1861480 | 0.82 | REN (0.53) | RENTSHR | |
| SCHEMBL1861476 | 0.82 | REN (0.53) | RENTSHR | |
| SCHEMBL1865929 | 0.82 | REN (0.53) | RENTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966139-A1 | ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070201-A1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |