Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 9/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969812 | 0.90 | REN (0.45) | RENKDM4EALDH1A1TSHRTDP1 | |
| SCHEMBL4973950 | 0.90 | REN (0.45) | RENKDM4EALDH1A1TSHRTDP1 | |
| SCHEMBL4973514 | 0.90 | REN (0.44) | RENKDM4E | |
| SCHEMBL4971183 | 0.85 | REN (0.45) | RENKDM4EALDH1A1TSHRTDP1 | |
| SCHEMBL4972473 | 0.83 | REN (0.43) | RENKDM4EALDH1A1TSHRTDP1 | |
| SCHEMBL1863705 | 0.83 | REN (0.54) | RENALDH1A1TSHR | |
| SCHEMBL1863699 | 0.83 | REN (0.54) | RENALDH1A1TSHR | |
| SCHEMBL1863701 | 0.83 | REN (0.54) | RENALDH1A1TSHR | |
| SCHEMBL4969868 | 0.83 | REN (0.43) | RENKDM4EALDH1A1TSHRTDP1 | |
| SCHEMBL5515790 | 0.82 | REN (0.54) | RENKDM4ENPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966139-A1 | ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070201-A1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |