Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.66 |
| ▸ | HTR1A | P08908 | 5/20 | 0.50 |
| ▸ | HTR2A | P28223 | 4/20 | 0.50 |
| ▸ | HTR1D | P28221 | 3/20 | 0.50 |
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
| ▸ | HTR2B | P41595 | 3/20 | 0.50 |
| ▸ | HTR1B | P28222 | 2/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | HTR5A | P47898 | 2/20 | 0.50 |
| ▸ | HTR1E | P28566 | 1/20 | 0.50 |
| ▸ | HTR1F | P30939 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970372 | 0.91 | HTR6 (0.75) | HTR6HTR1AHTR1DHTR1BMPO | |
| SCHEMBL4967334 | 0.88 | HTR6 (0.74) | HTR6HTR1AHTR2AHTR1DHTR2C | |
| SCHEMBL4970620 | 0.87 | HTR6 (0.84) | HTR6HTR1AHTR2AHTR1DHTR2C | |
| SCHEMBL3155934 | 0.85 | HTR6 (0.82) | HTR6HTR1AHTR2AHTR1DHTR2C | |
| SCHEMBL4970678 | 0.81 | HTR6 (0.61) | HTR6HTR1AHTR2AHTR1DHTR2C | |
| SCHEMBL4967568 | 0.80 | HTR6 (0.70) | HTR6HTR1AHTR2AHTR1DHTR2C | |
| SCHEMBL4970935 | 0.80 | HTR6 (0.54) | HTR6HTR1AHTR2AHTR1DHTR2C | |
| SCHEMBL1423485 | 0.79 | HTR6 (1.00) | HTR6HTR7HTR5A | |
| SCHEMBL4966738 | 0.79 | HTR6 (0.75) | HTR6HTR1AHTR2AHTR1DHTR1B | |
| SCHEMBL4969914 | 0.78 | HTR6 (0.67) | HTR6HTR1AHTR2AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626715-B1 | USE OF SULPHONAMIDE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE PROPHYLAXIS AND/OR TREATMENT OF DISORDERS OF FOOD INGESTION | ESTEVE LABOR DR (ES) | 2008-09-10 | — | — | EP | claimed |