Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.54 |
| ▸ | HTR1D | P28221 | 4/20 | 0.47 |
| ▸ | HTR1A | P08908 | 4/20 | 0.47 |
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | HTR5A | P47898 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR1E | P28566 | 1/20 | 0.47 |
| ▸ | HTR1F | P30939 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3154302 | 0.87 | HTR6 (0.69) | HTR6HTR7HTR5ALMNA | |
| SCHEMBL4970678 | 0.84 | HTR6 (0.61) | HTR6HTR1DHTR1AHTR1BHTR7 | |
| SCHEMBL4967334 | 0.81 | HTR6 (0.74) | HTR6HTR1DHTR1AHTR1BHTR7 | |
| SCHEMBL4969918 | 0.80 | HTR6 (0.66) | HTR6HTR1DHTR1AHTR1BHTR7 | |
| SCHEMBL4967568 | 0.77 | HTR6 (0.70) | HTR6HTR1DHTR1AHTR1BHTR7 | |
| SCHEMBL4970620 | 0.75 | HTR6 (0.84) | HTR6HTR1DHTR1AHTR1BHTR7 | |
| SCHEMBL3142938 | 0.72 | HTR6 (0.77) | HTR6HTR7HTR5A | |
| SCHEMBL4966738 | 0.72 | HTR6 (0.75) | HTR6HTR1DHTR1AHTR1BHTR2A | |
| SCHEMBL4971305 | 0.72 | HTR6 (0.54) | HTR6HTR1DHTR1AHTR1BHTR7 | |
| SCHEMBL4969914 | 0.72 | HTR6 (0.67) | HTR6HTR1DHTR1AHTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626715-B1 | USE OF SULPHONAMIDE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE PROPHYLAXIS AND/OR TREATMENT OF DISORDERS OF FOOD INGESTION | ESTEVE LABOR DR (ES) | 2008-09-10 | — | — | EP | claimed |