Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | HTR1D | P28221 | 3/20 | 0.46 |
| ▸ | HTR1B | P28222 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR1F | P30939 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3138627 | 0.86 | HTR6 (0.55) | HTR6MPOHTR1AHTR1DHTR1B | |
| SCHEMBL4970421 | 0.82 | HTR6 (0.50) | HTR6MPOHTR1AHTR1DHTR1B | |
| SCHEMBL3147357 | 0.80 | HTR6 (0.52) | HTR6MPOHTR1AHTR1DHTR1B | |
| SCHEMBL3147363 | 0.80 | HTR6 (0.52) | HTR6MPOHTR1AHTR1DHTR1B | |
| SCHEMBL5659589 | 0.77 | HTR6 (0.53) | HTR6MPOHTR1AHTR1DHTR1B | |
| SCHEMBL28805276 | 0.75 | HTR6 (0.62) | HTR6MPOKDM4EALDH1A1TDP1 | |
| SCHEMBL4004572 | 0.74 | HTR6 (0.54) | HTR6MPO | |
| SCHEMBL4968330 | 0.73 | HTR6 (0.61) | HTR6MPOHTR1AHTR1DHTR1B | |
| SCHEMBL8126815 | 0.72 | HTR6 (0.52) | HTR6HTR1AHTR1DHTR1BHTR2A | |
| Water SCHEMBL28867170 | 0.72 | HTR6 (0.80) | HTR6MPOKDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626715-B1 | USE OF SULPHONAMIDE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE PROPHYLAXIS AND/OR TREATMENT OF DISORDERS OF FOOD INGESTION | ESTEVE LABOR DR (ES) | 2008-09-10 | — | — | EP | claimed |