Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 5/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CTH | P32929 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL752297 | 0.91 | — | — | |
| SCHEMBL22927897 | 0.82 | RECQL (0.39) | EGLN1ALDH1A1LMNAMAPTRECQL | |
| Methyl Carbamate SCHEMBL6010335 | 0.82 | EGLN1 (0.50) | EGLN1ALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL31217764 | 0.81 | EGLN1 (0.33) | EGLN1RECQLEPHX1TSHR | |
| SCHEMBL8500219 | 0.79 | MEN1 (0.46) | EGLN1ALDH1A1LMNATDP1EPHX1 | |
| SCHEMBL1000860 | 0.79 | MEN1 (0.46) | EGLN1ALDH1A1LMNATDP1EPHX1 | |
| SCHEMBL1486144 | 0.79 | MEN1 (0.46) | EGLN1ALDH1A1LMNATDP1EPHX1 | |
| SCHEMBL26564366 | 0.79 | EGLN1 (0.39) | EGLN1ALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL999017 | 0.79 | MEN1 (0.46) | EGLN1ALDH1A1LMNATDP1EPHX1 | |
| SCHEMBL17850583 | 0.79 | EPHX1 (0.43) | LMNARECQLFAAHEPHX1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957518-A1 | NEW CYCLIC PEPTIDE COMPOUNDS | Astellas Pharma Inc. (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007049803-A1 | NEW CYCLIC PEPTIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2007-05-03 | — | — | WO | disclosed |