⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969965 | 0.91 | EGLN1 (0.50) | — | |
| Methyl Carbamate SCHEMBL6010335 | 0.91 | EGLN1 (0.50) | — | |
| SCHEMBL15190050 | 0.80 | EGLN1 (0.48) | — | |
| SCHEMBL9632175 | 0.78 | TET2 (0.58) | — | |
| SCHEMBL3269747 | 0.78 | — | — | |
| SCHEMBL1912605 | 0.77 | EGLN1 (0.63) | — | |
| SCHEMBL606069 | 0.77 | — | — | |
| SCHEMBL2221876 | 0.76 | — | — | |
| SCHEMBL293281 | 0.76 | — | — | |
| SCHEMBL7765947 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 370 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356888-A | Elastase inhibitors | FARMITALIA CARLO ERBA (IT) | 1994-10-18 | — | — | US | claimed |
| EP-0505413-B1 | BETA-LACTAM DERIVATIVES | ERBA CARLO SPA (IT) | 1994-08-31 | — | — | EP | claimed |
| EP-0378604-B1 | 1,1-DIOXO-CEPHEM-4-CARBOTHIOLIC ACID DERIVATIVES | ERBA CARLO SPA (IT) | 1994-03-02 | — | — | EP | claimed |
| EP-0378604-A1 | 1,1-DIOXO-CEPHEM-4-CARBOTHIOLIC ACID DERIVATIVES. | ERBA CARLO SPA (IT) | 1990-07-25 | — | — | EP | claimed |
| WO-1989010926-A1 | 1,1-DIOXO-CEPHEM-4-CARBOTHIOLIC ACID DERIVATIVES | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-11-16 | — | — | WO | claimed |
| US-20250367166-A1 | NEXT GENERATION DIPROVOCIMS THAT ACTIVATE THE INNATE AND ADAPTIVE IMMUNE RESPONSE | SCRIPPS RESEARCH INST (US) | 2025-12-04 | — | — | US | disclosed |
| EP-3882252-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2025-11-19 | — | — | EP | disclosed |
| US-20250276078-A1 | Camptothecin Derivative And Ligand-drug Conjugate Thereof | BAILI BIO CHENGDU PHARMACEUTICAL CO LTD (CN) | 2025-09-04 | — | — | US | disclosed |
| EP-3609888-B1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | LILLY CO ELI (US) | 2025-08-27 | — | — | EP | disclosed |
| EP-4596041-A2 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | Organovo, Inc. (US) | 2025-08-06 | — | — | EP | disclosed |
| US-12338251-B2 | Substituted macrocycles useful as kinase inhibitors | TELIGENE US LLC (US) | 2025-06-24 | — | — | US | disclosed |
| CN-112533927-B | Substituted macrocycles useful as kinase inhibitors | 苏州韬略生物科技股份有限公司 | 2025-06-17 | — | — | CN | disclosed |
| US-4797396-A | INHIBITION OF ELASTASE, ANTIBIOTICS | MERCK & CO., INC. (US) | 1989-01-10 | — | — | US | disclosed |
| EP-0267723-A2 | New substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents | MERCK & CO. INC. (US) | 1988-05-18 | — | — | EP | disclosed |
| US-4711886-A | β-lactam derivatives as anti-inflammatory and antidegenerative agents | MERCK & CO., INC. (US) | 1987-12-08 | — | — | US | disclosed |
| US-4699904-A | ANTIINFLAMMATORY AND ANTIDEGENERATIVE AGENTS | MERCK & CO., INC. (US) | 1987-10-13 | — | — | US | disclosed |
| US-4637999-A | PROTEASE INHIBITORS | MERCK & CO., INC. (US) | 1987-01-20 | — | — | US | disclosed |
| EP-0207447-A2 | Tetrazolyl derivatives of beta-lactams useful as elastase inhibitors | MERCK & CO. INC. (US) | 1987-01-07 | — | — | EP | disclosed |
| US-4623645-A | ELASTASE INHIBITORS | MERCK & CO., INC. (US) | 1986-11-18 | — | — | US | disclosed |
| US-4547371-A | Substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents | MERCK & CO., INC. (US) | 1985-10-15 | — | — | US | disclosed |