Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18117414 | 0.82 | EPHX1 (0.50) | EPHX1MCL1FAAHMMP1MMP2 | |
| SCHEMBL249164 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL9937866 | 0.79 | — | — | |
| SCHEMBL22927897 | 0.79 | RECQL (0.39) | EPHX1MCL1RECQLLMNATSHR | |
| SCHEMBL20054145 | 0.79 | PRSS1 (0.38) | EPHX1RECQLLMNATSHR | |
| SCHEMBL4969965 | 0.79 | EGLN1 (0.50) | EPHX1FAAHRECQLHPGDKMT2A | |
| SCHEMBL17850647 | 0.79 | EPHX1 (0.62) | EPHX1FAAHKMT2A | |
| SCHEMBL3984277 | 0.79 | TDP1 (0.46) | EPHX1KMT2ATSHR | |
| SCHEMBL13451466 | 0.78 | EPHX1 (0.40) | EPHX1MCL1RECQLSMN1; SMN2LMNA | |
| SCHEMBL15712063 | 0.77 | TDP1 (0.44) | EPHX1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10434106-B2 | Oxysterol-statin compounds for bone growth | WARSAW ORTHOPEDIC, INC. (US) | 2019-10-08 | — | — | US | disclosed |
| US-20190270767-A1 | OXYSTEROL-THERAPEUTIC AGENT DERIVATIVE FOR BONE HEALING | WARSAW ORTHOPEDIC INC (US) | 2019-09-05 | — | — | US | disclosed |
| US-10294264-B2 | Oxysterol-therapeutic agent derivative for bone healing | WARSAW ORTHOPEDIC, INC. (US) | 2019-05-21 | — | — | US | disclosed |
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |
| EP-2714036-B1 | SUBSITUTED ALIPHANES, CYCLOPHANES, HETERAPHANES, HETEROPHANES, HETERO-HETERAPHANES AND METALLOCENES USEFUL FOR TREATING HCV INFECTIONS | ACHILLION PHARMACEUTICALS INC (US) | 2016-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10294264-B2 | Oxysterol-therapeutic agent derivative for bone healing | OSBP2, OSBP, SOST | EPHX1 951/4885MCL1 1378/4885FAAH 3670/4885 |
| US-20190270767-A1 | OXYSTEROL-THERAPEUTIC AGENT DERIVATIVE FOR BONE HEALING | OSBP2, OSBP, SOST | EPHX1 951/4885MCL1 1378/4885FAAH 3670/4885 |
| US-10434106-B2 | Oxysterol-statin compounds for bone growth | HMGCR, SOST, OSBP2 | EPHX1 1118/4885MCL1 3828/4885FAAH 4316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.