Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.64 |
| ▸ | AR | P10275 | 2/20 | 0.60 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.52 |
| ▸ | IAPP | P10997 | 2/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252879 | 0.89 | AR (0.76) | ARPTPN5ABCG2CXCL12MAPT | |
| SCHEMBL11252878 | 0.89 | AR (0.76) | ARPTPN5ABCG2CXCL12MAPT | |
| SCHEMBL636137 | 0.82 | BACE1 (0.74) | BACE1ARIAPPNR1H4MAPT | |
| SCHEMBL10805789 | 0.81 | PTPN5 (0.65) | ARPTPN5CXCL12MAPTMAPK1 | |
| SCHEMBL10805785 | 0.81 | PTPN5 (0.65) | ARPTPN5CXCL12MAPTMAPK1 | |
| SCHEMBL471832 | 0.77 | BCHE (0.77) | BACE1ARIAPPNR1H4MAPT | |
| SCHEMBL10829866 | 0.77 | PTPN5 (0.73) | ARPTPN5ABCG2MAPTCHRNA7 | |
| SCHEMBL13857122 | 0.77 | PTPN5 (0.73) | ARPTPN5ABCG2MAPTCHRNA7 | |
| SCHEMBL25219942 | 0.76 | CXCL12 (0.63) | ARABCG2CXCL12NR1H4MAPT | |
| SCHEMBL13857110 | 0.75 | AR (1.00) | ARMAPTMAPK1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254658-B1 | REMEDIES FOR THE TREATMENT OF NERVE DIORDERS | TAKARA BIO INC (JP) | 2008-09-24 | — | — | EP | disclosed |